Gianfranco Alpini Selected Research

INCB 3284

7/2014

Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline.

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Gianfranco Alpini Research Topics

Disease

47	Fibrosis (Cirrhosis) 01/2023 - 05/2002
40	Cholestasis 01/2023 - 05/2002
36	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 02/2009
36	Inflammation (Inflammations) 01/2023 - 10/2004
35	Neoplasms (Cancer) 01/2022 - 12/2005
33	Cholangiocarcinoma 04/2021 - 06/2002
27	Liver Diseases (Liver Disease) 01/2023 - 10/2004
19	Sclerosing Cholangitis 01/2023 - 05/2002
16	Non-alcoholic Fatty Liver Disease 01/2023 - 12/2012
16	Hyperplasia 01/2022 - 05/2007
8	Carcinogenesis 11/2021 - 05/2008
7	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2021 - 09/2012
6	Disease Progression 08/2023 - 05/2008
6	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 08/2023 - 05/2002
5	Hepatocellular Carcinoma (Hepatoma) 10/2022 - 04/2006
5	Fatty Liver 10/2021 - 02/2014
5	Liver Neoplasms (Liver Cancer) 01/2021 - 04/2006
4	Obesity 01/2022 - 12/2015
4	Necrosis 05/2015 - 10/2004
3	End Stage Liver Disease 08/2023 - 05/2002
3	Cystic Fibrosis (Mucoviscidosis) 01/2023 - 04/2010
3	Insulin Resistance 01/2021 - 12/2018
3	Body Weight (Weight, Body) 01/2018 - 08/2009
3	Autosomal Dominant Polycystic Kidney (ADPKD) 11/2016 - 02/2008
3	Cysts 11/2016 - 02/2008
3	Fistula 06/2014 - 04/2002
2	Pruritus (Itching) 08/2023 - 07/2012
2	Autoimmune Diseases (Autoimmune Disease) 08/2023 - 07/2017
2	Colitis 04/2023 - 11/2013
2	Cholangitis 01/2023 - 01/2023
2	Alcoholic Fatty Liver 01/2022 - 01/2020
2	Neoplasm Metastasis (Metastasis) 07/2021 - 04/2006

Drug/Important Bio-Agent (IBA)

19	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 05/2002
16	Secretin FDA Link 01/2023 - 04/2003
16	Histamine (Histamine Dihydrochloride)FDA Link 01/2023 - 06/2010
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 12/2005
13	Proteins (Proteins, Gene)FDA Link 11/2020 - 05/2007
13	MicroRNAs (MicroRNA)IBA 11/2020 - 12/2011
12	secretin receptorIBA 01/2023 - 04/2010
12	MelatoninIBA 01/2022 - 10/2011
12	CytokinesIBA 01/2021 - 07/2003
9	Messenger RNA (mRNA)IBA 04/2023 - 05/2006
9	Hormones (Hormone)IBA 01/2019 - 07/2007
8	EnzymesIBA 01/2023 - 11/2008
8	Bicarbonates (Hydrogen Carbonate)IBA 01/2023 - 04/2002
7	CollagenIBA 01/2022 - 12/2005
7	Phosphotransferases (Kinase)IBA 01/2021 - 07/2013
7	MorpholinosIBA 11/2020 - 01/2017
6	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2018 - 02/2008
5	LipidsIBA 10/2021 - 04/2007
5	FructoseIBA 01/2021 - 01/2018
5	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2018
5	Adenosine (Adenocard)FDA LinkGeneric 12/2018 - 05/2007
4	Taurocholic Acid (Sodium Taurocholate)IBA 01/2023 - 05/2007
4	CholesterolIBA 01/2023 - 12/2012
4	Chloride-Bicarbonate AntiportersIBA 01/2023 - 04/2010
4	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022 - 06/2002
4	Substance PIBA 11/2020 - 08/2011
4	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 01/2005
4	Vascular Endothelial Growth Factor CIBA 01/2020 - 12/2005
4	Histamine Receptors (Histamine Receptor)IBA 01/2018 - 10/2009
4	EndocannabinoidsIBA 01/2009 - 04/2007
4	Estrogens (Estrogen)FDA Link 02/2008 - 07/2002
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 04/2020
3	Peptides (Polypeptides)IBA 01/2023 - 04/2015
3	Ethanol (Ethyl Alcohol)IBA 01/2023 - 02/2014
3	DesminIBA 01/2023 - 01/2020
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2021 - 05/2010
3	Fast GreenIBA 01/2021 - 10/2016
3	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 11/2020 - 08/2011
3	Carboxy-LyasesIBA 01/2020 - 01/2018
3	Monoamine Oxidase (MAO)IBA 01/2020 - 11/2008
3	Histidine (L-Histidine)FDA Link 01/2020 - 01/2018
3	Arylalkylamine N-AcetyltransferaseIBA 01/2019 - 11/2014
3	NF-kappa B (NF-kB)IBA 01/2019 - 08/2009
3	Fibronectins (Fibronectin)IBA 01/2018 - 10/2016
3	Gonadotropin-Releasing Hormone (GnRH)FDA Link 11/2017 - 04/2015
3	Gonadal Steroid Hormones (Sex Hormones)IBA 10/2017 - 07/2009
3	Histidine DecarboxylaseIBA 10/2016 - 05/2012
3	ChemokinesIBA 01/2016 - 08/2009
3	NeuropeptidesIBA 08/2011 - 07/2008
3	anandamide (arachidonylethanolamide)IBA 01/2009 - 04/2007
2	AntigensIBA 08/2023 - 01/2017
2	Lipid NanoparticlesIBA 04/2023 - 01/2022
2	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2023 - 12/2005
2	Therapeutic UsesIBA 10/2022 - 10/2017
2	Adenosine Monophosphate (AMP)IBA 01/2022 - 07/2013
2	Choline (Choline Chloride)IBA 01/2022 - 10/2021
2	indoleIBA 01/2022 - 10/2020
2	Methionine (L-Methionine)FDA Link 01/2022 - 10/2021
2	Cholinergic Agents (Cholinergics)IBA 01/2022 - 10/2007
2	Melatonin Receptors (Melatonin Receptor)IBA 01/2022 - 10/2011
2	Biomarkers (Surrogate Marker)IBA 07/2021 - 12/2019

Therapy/Procedure

24	Therapeutics 08/2023 - 04/2006
21	Ligation 01/2019 - 10/2004
5	Liver Transplantation 08/2023 - 05/2002
3	Denervation 01/2022 - 05/2007
2	Immunotherapy 01/2022 - 01/2020
2	Drug Therapy (Chemotherapy) 07/2021 - 11/2008
2	Radiotherapy 07/2021 - 11/2008